Thiotepa FDA Link Generic

A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Also Known As:

Triethylenethiophosphoramide; AI3-24916; Girostan; NSC-6396; Tespa; Tespamin; Tris(1-aziridinyl)phosphine Sulfide; AI3 24916; AI324916; NSC 6396; NSC6396; Thio Tepa; Thio-Tepa; Thiophosphamide; Aziridine, 1,1',1''-phosphinothioylidynetris-

Pharmalogical Action Categories:

Antineoplastic Agents, Alkylating
Myeloablative Agonists

Organic Chemicals: 140
- Organophosphorus Compounds: 307
  - Phosphoramides: 8
    - Thiotepa: 1150
Heterocyclic Compounds: 207
- 1-Ring Heterocyclic Compounds
  - Azirines
    - Aziridines: 14
      - Triethylenephosphoramide: 79
        Thiotepa: 1150

Louise M Hopkins Selected Research

Louise M Hopkins Research Topics

Disease

Drug/Important Bio-Agent (IBA)